Nsg1 | neuron specific gene family member 1

GeneMGI:109149Synonyms: NEEP21, m234, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Vision/eye Hematopoietic system Cardiovascular system

17 No significant impact

3 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

eye hemorrhage1 supporting datasetNsg1tm1.1(KOMP)VlcghomozygoteEarly adult1.3x10-5 
increased mean platelet volume1 supporting datasetNsg1tm1.1(KOMP)VlcghomozygoteEarly adult3.3x10-5 
increased monocyte cell number1 supporting datasetNsg1tm1.1(KOMP)VlcghomozygoteEarly adult6.72x10-7 
increased lymphocyte cell number1 supporting datasetNsg1tm1.1(KOMP)VlcghomozygoteEarly adult1.22x10-5 
increased leukocyte cell number1 supporting datasetNsg1tm1.1(KOMP)VlcghomozygoteEarly adult3.65x10-5 
increased basophil cell number1 supporting datasetNsg1tm1.1(KOMP)VlcghomozygoteEarly adult1.22x10-5 
increased neutrophil cell number1 supporting datasetNsg1tm1.1(KOMP)VlcghomozygoteEarly adult2.62x10-5 
increased eosinophil cell number1 supporting datasetNsg1tm1.1(KOMP)VlcghomozygoteEarly adult1.06x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nsg1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Nsg1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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