Adcy9 | adenylate cyclase 9

GeneMGI:108450Synonyms: D16Wsu65e, ACtp10

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetAdcy9tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased circulating insulin level1 supporting datasetAdcy9tm1b(EUCOMM)WtsiheterozygoteEarly adult1.07x10-33 
decreased circulating chloride level1 supporting datasetAdcy9tm1b(EUCOMM)WtsiheterozygoteEarly adult9.83x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Adcy9tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Adcy9tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Adcy9tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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