Slbp | stem-loop binding protein

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging

16 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
25Embryo tissues

Phenotypes

increased circulating bilirubin level1 supporting datasetSlbptm1.1(KOMP)VlcgheterozygoteEarly adult1.41x10-5 
embryonic lethality prior to tooth bud stage1 supporting datasetSlbptm1.1(KOMP)VlcghomozygoteE12.5N/A * 
increased mean corpuscular hemoglobin1 supporting datasetSlbptm1.1(KOMP)VlcgheterozygoteEarly adult1.77x10-5 
preweaning lethality, complete penetrance1 supporting datasetSlbptm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
hyperactivity1 supporting datasetSlbptm1.1(KOMP)VlcgheterozygoteEarly adult3.64x10-5 
increased circulating aspartate transaminase level1 supporting datasetSlbptm1.1(KOMP)VlcgheterozygoteEarly adult1.83x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slbptm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Slbptm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Slbptm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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