Mlx | MAX-like protein X

GeneMGI:108398Synonyms: bHLHd13, Tcfl4, +1 more

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Adipose tissue Growth/size/body region Hematopoietic system Skeleton Renal/urinary system

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

1Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:

Life Stage:



increased circulating sodium level	1 supporting dataset	Mlx^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.97x10^-6
decreased total body fat amount	1 supporting dataset	Mlx^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	4.82x10^-5
decreased mean corpuscular volume	1 supporting dataset	Mlx^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	3.76x10^-10
increased bone mineral content	1 supporting dataset	Mlx^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	1.71x10^-5
increased fasting circulating glucose level	1 supporting dataset	Mlx^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	6.71x10^-7
increased urine glucose level	1 supporting dataset	Mlx^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.73x10^-5
male infertility	1 supporting dataset	Mlx^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased lean body mass	1 supporting dataset	Mlx^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	4.07x10^-5
decreased circulating glucose level	1 supporting dataset	Mlx^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	2.01x10^-6
decreased mean corpuscular hemoglobin	1 supporting dataset	Mlx^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	5.86x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mlx.

Associated images

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Histopathology

There is no histopathology data found for Mlx.

IMPC related publications

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External links

No external links available for Mlx.

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*Mlx^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Mlx^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Mlx^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Mlx^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mlx^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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