Emd | emerin

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Behavior/neurological

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal seminal vesicle morphology1 supporting datasetEmdem1(IMPC)KmpchemizygoteLate adultN/A * 
increased circulating phosphate level1 supporting datasetEmdem1(IMPC)KmpchemizygoteEarly adult1.63x10-8 
increased circulating phosphate level1 supporting datasetEmdem1(IMPC)KmpchomozygoteEarly adult1.79x10-7 
enhanced cued conditioning behavior1 supporting datasetEmdem1(IMPC)KmpchomozygoteLate adult8.86x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Emdem1(IMPC)KmpcIndelmouse
Emdtm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Emdtm455032(Ifitm2_intron_L1L2_GT2_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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