Frrs1 | ferric-chelate reductase 1

GeneMGI:108076Synonyms: Sdfr2

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Frrs1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased food intake	1 supporting dataset	Frrs1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	7.27x10^-5
increased circulating free fatty acids level	1 supporting dataset	Frrs1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.07x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Frrs1.

Associated images

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Histopathology

There is no histopathology data found for Frrs1.

IMPC related publications

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External links

No external links available for Frrs1.

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*Frrs1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Frrs1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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