Cxcl1 | C-X-C motif chemokine ligand 1

GeneMGI:108068Synonyms: Gro1, KC/GRO-alpha, +5 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Vision/eye Hematopoietic system Skeleton

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged lymph nodes	1 supporting dataset	Cxcl1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Cxcl1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased bone mineral content	1 supporting dataset	Cxcl1^em1(IMPC)Mbp	homozygote	Early adult	2.93x10^-5
abnormal lymph node morphology	1 supporting dataset	Cxcl1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased monocyte cell number	1 supporting dataset	Cxcl1^em1(IMPC)Mbp	homozygote	Early adult	2.85x10^-5
decreased bone mineral density	1 supporting dataset	Cxcl1^em1(IMPC)Mbp	homozygote	Early adult	4.18x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cxcl1.

Associated images

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Histopathology

There is no histopathology data found for Cxcl1.

IMPC related publications

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External links

No external links available for Cxcl1.

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*Cxcl1^em1(IMPC)Mbp*	Whole-gene deletion	‌	mouse

My Genes