Cd36 | CD36 molecule

GeneMGI:107899Synonyms: Scarb3, FAT, +1 more

Physiological systems

20 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Growth/size/body region Nervous system Vision/eye Liver/biliary system Hematopoietic system Skeleton Cardiovascular system

10 No significant impact

4 Not tested

Gene metrics:19Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged spleen2 supporting datasetsCd36em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal brain morphology1 supporting datasetCd36em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal vitreous body morphology1 supporting datasetCd36em1(IMPC)MbphomozygoteEarly adult8.92x10-5 
eye hemorrhage1 supporting datasetCd36em1(IMPC)MbphomozygoteLate adult2.16x10-5 
decreased fasting circulating glucose level1 supporting datasetCd36em1(IMPC)MbphomozygoteEarly adult1.53x10-7 
cataract1 supporting datasetCd36em1(IMPC)MbphomozygoteEarly adult6.42x10-5 
decreased circulating triglyceride level1 supporting datasetCd36em1(IMPC)MbphomozygoteLate adult1.07x10-7 
abnormal spleen morphology2 supporting datasetsCd36em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged liver1 supporting datasetCd36em1(IMPC)MbphomozygoteLate adultN/A * 
increased heart weight1 supporting datasetCd36em1(IMPC)MbphomozygoteLate adult5.63x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cd36em1(IMPC)MbpExon Deletionmouse
Cd36tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Cd36tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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