Gp1bb | glycoprotein Ib, beta polypeptide

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Hematopoietic system

18 No significant impact

3 Not tested

Gene metrics:7Significant phenotypes
5Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

thrombocytopenia1 supporting datasetGp1bbtm1.1(KOMP)VlcghomozygoteEarly adult5.38x10-11 
abnormal uterus morphology1 supporting datasetGp1bbtm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased mean corpuscular volume1 supporting datasetGp1bbtm1.1(KOMP)VlcghomozygoteEarly adult5.26x10-6 
hydrometra1 supporting datasetGp1bbtm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased mean platelet volume1 supporting datasetGp1bbtm1.1(KOMP)VlcghomozygoteEarly adult1.02x10-21 
abnormal testis morphology1 supporting datasetGp1bbtm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
small testis1 supporting datasetGp1bbtm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gp1bbtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Gp1bbtm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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