Ctsk | cathepsin K
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Limbs/digits/tail Nervous system Skeleton
12 No significant impact
7 Not tested
Data collections
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased bone mineral density | 1 supporting dataset | Ctsktm1b(EUCOMM)Hmgu | homozygote | Early adult | 3.53x10-9 | ||
| decreased prepulse inhibition | 3 supporting datasets | Ctsktm1b(EUCOMM)Hmgu | homozygote | Early adult | 6.64x10-10 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Ctsktm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.52x10-5 | ||
| short tibia | 1 supporting dataset | Ctsktm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.11x10-12 | ||
| abnormal uterus morphology | 1 supporting dataset | Ctsktm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * |
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External links
No external links available for Ctsk.
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| Ctsktm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Ctsktm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Ctsktm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ctsktm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |