Serpina5 | serine (or cysteine) peptidase inhibitor, clade A, member 5

GeneMGI:107817Synonyms: alpha-1 antiproteinase, Pci, +2 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Reproductive system Growth/size/body region Renal/urinary system

17 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

male infertility1 supporting datasetSerpina5em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetSerpina5em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged kidney1 supporting datasetSerpina5em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Serpina5em1(IMPC)MbpExon Deletionmouse
Serpina5tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Serpina5tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Serpina5tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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