Myo1a | myosin IA

GeneMGI:107732Synonyms: Myhl, BBM-I, +1 more

Physiological systems

14 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

12 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



limb grasping	1 supporting dataset	Myo1a^em1(IMPC)Bay	homozygote	Early adult	5.95x10^-9
abnormal eye anterior chamber depth	1 supporting dataset	Myo1a^em1(IMPC)Bay	homozygote	Early adult	2.28x10^-14
increased cornea thickness	1 supporting dataset	Myo1a^em1(IMPC)Bay	homozygote	Early adult	4.74x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Myo1a.

Associated images

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Histopathology

There is no histopathology data found for Myo1a.

IMPC related publications

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External links

No external links available for Myo1a.

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*Myo1a^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Myo1a^{tm1(EGFP/cre/ERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Myo1a^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Myo1a^{tm1.1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	ES Cell
*Myo1a^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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