Dnah5 | dynein, axonemal, heavy chain 5

GeneMGI:107718Synonyms: Dnahc5, b2b1154Clo, +5 more

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

19 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	2 supporting datasets	Dnah5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Dnah5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating calcium level	1 supporting dataset	Dnah5^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	2.76x10^-6
increased blood urea nitrogen level	1 supporting dataset	Dnah5^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	9.3x10^-5
increased circulating total protein level	1 supporting dataset	Dnah5^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.52x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dnah5.

Associated images

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Histopathology

There is no histopathology data found for Dnah5.

IMPC related publications

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External links

No external links available for Dnah5.

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*Dnah5^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dnah5^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dnah5^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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