Ifngr1 | interferon gamma receptor 1

GeneMGI:107655Synonyms: Ifgr, IFN-gammaR, +4 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Integument Vision/eye Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

9Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	3 supporting datasets	Ifngr1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Ifngr1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Ifngr1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Ifngr1^em1(IMPC)Mbp	homozygote	Early adult	9.61x10^-6
cataract	1 supporting dataset	Ifngr1^em1(IMPC)Mbp	homozygote	Early adult	8.73x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ifngr1.

Associated images

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Histopathology

There is no histopathology data found for Ifngr1.

IMPC related publications

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External links

No external links available for Ifngr1.

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*Ifngr1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Ifngr1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ifngr1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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