Mvk | mevalonate kinase
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland Embryo Growth/size/body region Vision/eye Mortality/aging
14 No significant impact
4 Not tested
Data collections
Gene metrics:9Significant phenotypes
7Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Mvkem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| small seminal vesicle | 1 supporting dataset | Mvkem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| microphthalmia | 1 supporting dataset | Mvkem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| small epididymis | 1 supporting dataset | Mvkem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Mvkem1(IMPC)Tcp | homozygote | E9.5 | N/A * | ||
| hydrometra | 1 supporting dataset | Mvkem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Mvkem1(IMPC)Tcp | heterozygote | E9.5 | N/A * | ||
| small testis | 1 supporting dataset | Mvkem1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Mvkem1(IMPC)Tcp | homozygote | E12.5 | N/A * |
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External links
No external links available for Mvk.
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| Mvkem1(IMPC)Tcp | Exon Deletion | | mouse |