Xiap | X-linked inhibitor of apoptosis

GeneMGI:107572Synonyms: Api3, IAP3, +4 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



absent testes	1 supporting dataset	Xiap^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	3.83x10^-11
increased IgG1 level	1 supporting dataset	Xiap^{tm1a(EUCOMM)Hmgu}	homozygote	Early adult	2.19x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Xiap.

Associated images

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Histopathology

There is no histopathology data found for Xiap.

IMPC related publications

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External links

No external links available for Xiap.

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*Xiap^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Xiap^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Xiap^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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