Plcb2 | phospholipase C, beta 2

GeneMGI:107465Synonyms: B230205M18Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Immune system Growth/size/body region Respiratory system Hematopoietic system Behavior/neurological

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vocalization	1 supporting dataset	Plcb2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.56x10^-6
abnormal spleen morphology	1 supporting dataset	Plcb2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased pulmonary ventilation	1 supporting dataset	Plcb2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.4x10^-5
decreased locomotor activity	2 supporting datasets	Plcb2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.77x10^-5
enlarged spleen	1 supporting dataset	Plcb2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
male infertility	1 supporting dataset	Plcb2^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Plcb2.

Associated images

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Histopathology

There is no histopathology data found for Plcb2.

IMPC related publications

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External links

No external links available for Plcb2.

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*Plcb2^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Plcb2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Plcb2^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Plcb2^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Plcb2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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