Supt4a | SPT4A, DSIF elongation factor subunit
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Hematopoietic system Mortality/aging
17 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
preweaning lethality, complete penetrance | 3 supporting datasets | Supt4atm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
decreased mean corpuscular hemoglobin concentration | 1 supporting dataset | Supt4atm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.62x10-6 | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Supt4atm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Supt4atm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * |
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External links
No external links available for Supt4a.
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Supt4atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Supt4atm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Supt4atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |