Tnfsf10 | tumor necrosis factor (ligand) superfamily, member 10

GeneMGI:107414Synonyms: Trail, APO-2L, +1 more

Physiological systems

21 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

20 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes



increased circulating alanine transaminase level	1 supporting dataset		Tnfsf10^{tm1b(KOMP)Wtsi}	homozygote	Early adult		3.09x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tnfsf10.

Associated images

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Histopathology

There is no histopathology data found for Tnfsf10.

IMPC related publications

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External links

No external links available for Tnfsf10.

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*Tnfsf10^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Tnfsf10^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Tnfsf10^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Tnfsf10^{tm96621(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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