Il17ra | interleukin 17 receptor A

GeneMGI:107399Synonyms: VDw217, Il17r

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Integument Endocrine/exocrine gland Liver/biliary system Behavior/neurological Skeleton

14 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased grip strength	4 supporting datasets	Il17ra^em1(IMPC)Mbp	homozygote	Early adult	1.39x10^-7
small liver	1 supporting dataset	Il17ra^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Il17ra^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal gait	1 supporting dataset	Il17ra^em1(IMPC)Mbp	homozygote	Early adult	6.64x10^-12
abnormal uterus morphology	1 supporting dataset	Il17ra^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased exploration in new environment	1 supporting dataset	Il17ra^em1(IMPC)Mbp	homozygote	Early adult	3.53x10^-5
abnormal skin morphology	2 supporting datasets	Il17ra^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased vertical activity	1 supporting dataset	Il17ra^em1(IMPC)Mbp	homozygote	Early adult	1.1x10^-23
abnormal ovary morphology	1 supporting dataset	Il17ra^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased bone mineral content	1 supporting dataset	Il17ra^em1(IMPC)Mbp	homozygote	Early adult	4.42x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Il17ra.

Associated images

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Histopathology

There is no histopathology data found for Il17ra.

IMPC related publications

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External links

No external links available for Il17ra.

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*Il17ra^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Il17ra^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Il17ra^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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