Dnm1 | dynamin 1

GeneMGI:107384Synonyms: Ftfl, dynamin 1

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Embryo Nervous system Mortality/aging Cardiovascular system

16 No significant impact

4 Not tested

Gene metrics:3Significant phenotypes
4Associated diseases
Expression examined in:73Adult tissues
104Embryo tissues

Phenotypes

hemorrhage1 supporting datasetDnm1tm1.1(KOMP)VlcghomozygoteE15.5N/A * 
spina bifida1 supporting datasetDnm1tm1.1(KOMP)VlcgheterozygoteE15.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetDnm1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
hemorrhage1 supporting datasetDnm1tm1.1(KOMP)VlcgheterozygoteE15.5N/A * 
spina bifida1 supporting datasetDnm1tm1.1(KOMP)VlcghomozygoteE15.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dnm1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Dnm1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Dnm1tm51066(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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