Ctsh | cathepsin H
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Vision/eye Skeleton
16 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:50Adult tissues
0Embryo tissues
| decreased total retina thickness | 1 supporting dataset | Ctshtm1b(KOMP)Wtsi | homozygote | Early adult | 3.23x10-5 | ||
| abnormal eye anterior chamber depth | 1 supporting dataset | Ctshtm1b(KOMP)Wtsi | homozygote | Early adult | 2.1x10-5 | ||
| abnormal retina inner nuclear layer morphology | 1 supporting dataset | Ctshtm1b(KOMP)Wtsi | homozygote | Early adult | 8.79x10-6 | ||
| increased bone mineral density | 1 supporting dataset | Ctshtm1b(KOMP)Wtsi | homozygote | Early adult | 2.9x10-6 | ||
| abnormal retina outer nuclear layer morphology | 1 supporting dataset | Ctshtm1b(KOMP)Wtsi | homozygote | Early adult | 2.1x10-6 | ||
| increased bone mineral content | 2 supporting datasets | Ctshtm1b(KOMP)Wtsi | homozygote | Early adult | 2x10-5 |
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External links
No external links available for Ctsh.
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| Ctshtm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ctshtm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Ctshtm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Ctshtm42823(L1L2_st0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |