Serpinb9 | serine (or cysteine) peptidase inhibitor, clade B, member 9

GeneMGI:106603Synonyms: Spi6, ovalbumin, +1 more

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Vision/eye Respiratory system Hematopoietic system Skeleton Cardiovascular system

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal bone structure	1 supporting dataset	Serpinb9^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Serpinb9^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased airway resistance	4 supporting datasets	Serpinb9^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.23x10^-11
abnormal eye morphology	1 supporting dataset	Serpinb9^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
cornea opacity	1 supporting dataset	Serpinb9^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.25x10^-6
abnormal skin morphology	1 supporting dataset	Serpinb9^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased effector memory T-helper cell number	1 supporting dataset	Serpinb9^{em1(IMPC)Ccpcz}	homozygote	Early adult	7.46x10^-5
abnormal heart morphology	1 supporting dataset	Serpinb9^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Serpinb9^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Serpinb9.

Associated images

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Histopathology

There is no histopathology data found for Serpinb9.

IMPC related publications

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External links

No external links available for Serpinb9.

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*Serpinb9^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Serpinb9^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Serpinb9^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Serpinb9^{tm38935(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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