Has1 | hyaluronan synthase 1

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

17 No significant impact

5 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

decreased eosinophil cell number1 supporting datasetHas1tm1b(KOMP)WtsihomozygoteEarly adult8.46x10-10 
increased basophil cell number1 supporting datasetHas1tm1b(KOMP)WtsihomozygoteEarly adult3.85x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Has1tm115308(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Has1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Has1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Has1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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