Dbndd2 | dysbindin domain containing 2

GeneMGI:106562Synonyms: 2900022J10Rik, 1110017A21Rik, +3 more

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Nervous system Hematopoietic system Skeleton Renal/urinary system

10 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	4 supporting datasets	Dbndd2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.64x10^-9
thrombocytosis	1 supporting dataset	Dbndd2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	7.6x10^-5
decreased circulating creatinine level	1 supporting dataset	Dbndd2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	9.18x10^-5
small epididymis	1 supporting dataset	Dbndd2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
short tibia	1 supporting dataset	Dbndd2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.46x10^-6
small testis	1 supporting dataset	Dbndd2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Dbndd2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dbndd2.

Associated images

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Histopathology

There is no histopathology data found for Dbndd2.

IMPC related publications

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External links

No external links available for Dbndd2.

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*Dbndd2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Dbndd2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dbndd2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Dbndd2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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