Dbndd2 | dysbindin domain containing 2

GeneMGI:106562Synonyms: 2900022J10Rik, 1110017A21Rik, +3 more

Physiological systems

19 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Growth/size/body region Limbs/digits/tail Nervous system Hematopoietic system Skeleton Renal/urinary system

10 No significant impact

5 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition4 supporting datasetsDbndd2tm1b(EUCOMM)WtsihomozygoteEarly adult9.64x10-9 
thrombocytosis1 supporting datasetDbndd2tm1b(EUCOMM)WtsihomozygoteEarly adult7.6x10-5 
decreased circulating creatinine level1 supporting datasetDbndd2tm1b(EUCOMM)WtsihomozygoteEarly adult9.18x10-5 
small epididymis1 supporting datasetDbndd2tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
short tibia1 supporting datasetDbndd2tm1b(EUCOMM)WtsihomozygoteEarly adult3.46x10-6 
small testis1 supporting datasetDbndd2tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
enlarged urinary bladder1 supporting datasetDbndd2tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dbndd2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Dbndd2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dbndd2tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Dbndd2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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