Ccdc92 | coiled-coil domain containing 92

GeneMGI:106485Synonyms: D5Bwg0834e

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Hearing/vestibular/ear Nervous system Behavior/neurological Skeleton Mortality/aging

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



decreased grip strength	1 supporting dataset	Ccdc92^{tm1b(KOMP)Mbp}	homozygote	Early adult	3.25x10^-5
abnormal auditory brainstem response	1 supporting dataset	Ccdc92^{tm1b(KOMP)Mbp}	homozygote	Early adult	1.54x10^-5
increased bone mineral density	1 supporting dataset	Ccdc92^{tm1a(KOMP)Mbp}	homozygote	Early adult	7.89x10^-5
preweaning lethality, incomplete penetrance	2 supporting datasets	Ccdc92^{tm1b(KOMP)Mbp}	homozygote	Early adult	N/A ^*
increased circulating serum albumin level	1 supporting dataset	Ccdc92^{tm1a(KOMP)Mbp}	homozygote	Early adult	9.86x10^-5
decreased circulating cholesterol level	1 supporting dataset	Ccdc92^{tm1b(KOMP)Mbp}	homozygote	Early adult	1.14x10^-5
decreased brain weight	1 supporting dataset	Ccdc92^{tm1b(KOMP)Mbp}	homozygote	Early adult	4.9x10^-5
increased blood urea nitrogen level	1 supporting dataset	Ccdc92^{tm1a(KOMP)Mbp}	homozygote	Early adult	5.03x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ccdc92.

Associated images

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Histopathology

There is no histopathology data found for Ccdc92.

IMPC related publications

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External links

No external links available for Ccdc92.

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*Ccdc92^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ccdc92^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ccdc92^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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