Rnasek | ribonuclease, RNase K

GeneMGI:106369Synonyms: D11Bwg0434e, 2310033H11Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

16 No significant impact

6 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased circulating alanine transaminase level1 supporting datasetRnasektm1b(EUCOMM)WtsiheterozygoteEarly adult3.15x10-9 
preweaning lethality, complete penetrance1 supporting datasetRnasektm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rnasektm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Rnasektm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Rnasektm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Rnasektm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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