Vps25 | vacuolar protein sorting 25
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Adipose tissue Embryo Growth/size/body region Mortality/aging Cardiovascular system
14 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:42Adult tissues
29Embryo tissues
| decreased lean body mass | 1 supporting dataset | Vps25tm1.1(KOMP)Vlcg | heterozygote | Early adult | 6.6x10-5 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Vps25tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Vps25tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
| increased total body fat amount | 1 supporting dataset | Vps25tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.07x10-6 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Vps25tm1.1(KOMP)Vlcg | homozygote | E12.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Vps25tm1.1(KOMP)Vlcg | heterozygote | E9.5 | N/A * | ||
| decreased heart weight | 1 supporting dataset | Vps25tm1.1(KOMP)Vlcg | heterozygote | Early adult | 8.31x10-5 |
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External links
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| Vps25tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Vps25tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Vps25tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Vps25tm290428(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Vps25tm47348(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |