Ermp1 | endoplasmic reticulum metallopeptidase 1

GeneMGI:106250Synonyms: D19Wsu12e, D19Ertd410e, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Cardiovascular system

15 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

increased circulating sodium level1 supporting datasetErmp1tm1.1(KOMP)VlcghomozygoteEarly adult2.94x10-5 
decreased circulating calcium level1 supporting datasetErmp1tm1.1(KOMP)VlcghomozygoteEarly adult7.29x10-6 
increased circulating chloride level1 supporting datasetErmp1tm1.1(KOMP)VlcghomozygoteEarly adult7.34x10-5 
shortened PQ interval1 supporting datasetErmp1tm1.1(KOMP)VlcghomozygoteEarly adult1.14x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ermp1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Ermp1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Ermp1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ermp1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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