Cox7a2l | cytochrome c oxidase subunit 7A2 like

GeneMGI:106015Synonyms: COX7AR, SIG81, +4 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Cardiovascular system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity2 supporting datasetsCox7a2lem1(IMPC)JhomozygoteEarly adult6.78x10-5 
prolonged RR interval1 supporting datasetCox7a2lem1(IMPC)JhomozygoteEarly adult4.56x10-5 
decreased startle reflex1 supporting datasetCox7a2lem1(IMPC)JhomozygoteEarly adult3.35x10-5 
decreased exploration in new environment1 supporting datasetCox7a2lem1(IMPC)JheterozygoteEarly adult3.14x10-8 
decreased exploration in new environment1 supporting datasetCox7a2lem1(IMPC)JhomozygoteEarly adult1.61x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cox7a2lem1(IMPC)JWhole-gene deletionmouse
Cox7a2ltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cox7a2ltm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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