Fer | FER tyrosine kinase

GeneMGI:105917Synonyms: Fert, C330004K01Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

13 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological Skeleton Mortality/aging Craniofacial Renal/urinary system

6 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetFerem1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetFerem1(IMPC)TcpheterozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetFerem1(IMPC)TcphomozygoteEarly adult1.24x10-6 
abnormal sternum morphology1 supporting datasetFerem1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetFerem1(IMPC)TcphomozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance1 supporting datasetFerem1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal snout morphology1 supporting datasetFerem1(IMPC)TcphomozygoteEarly adult5.96x10-5 
abnormal retina morphology1 supporting datasetFerem1(IMPC)TcpheterozygoteEarly adult6.83x10-10 
abnormal skin morphology1 supporting datasetFerem1(IMPC)TcphomozygoteEarly adultN/A * 
increased spleen weight1 supporting datasetFerem1(IMPC)TcpheterozygoteEarly adult6.24x10-17 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ferem1(IMPC)TcpIntra-exon deletionmouse

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