Lama5 | laminin, alpha 5

GeneMGI:105382

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Cardiovascular system Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

3Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



enlarged heart	1 supporting dataset	Lama5^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Lama5^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lama5.

Associated images

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Histopathology

There is no histopathology data found for Lama5.

IMPC related publications

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External links

No external links available for Lama5.

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*Lama5^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Lama5^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Lama5^{tm1c(KOMP)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Lama5^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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