Il6ra | interleukin 6 receptor, alpha

GeneMGI:105304Synonyms: CD126, Il6r, +2 more

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Reproductive system Hematopoietic system

19 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

4Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



increased red blood cell distribution width	1 supporting dataset	Il6ra^{em1(IMPC)Wtsi}	homozygote	Early adult	6.84x10^-5
hydrometra	1 supporting dataset	Il6ra^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Il6ra.

Associated images

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Histopathology

There is no histopathology data found for Il6ra.

IMPC related publications

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External links

No external links available for Il6ra.

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*Il6ra^{em1(IMPC)Wtsi}*	Point Mutation	‌	mouse
*Il6ra^{em2(IMPC)Wtsi}*	Point Mutation	‌	mouse
*Il6ra^{em3(IMPC)Wtsi}*		‌	mouse
*Il6ra^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Il6ra^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Il6ra^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Il6ra^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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