Atf6b | activating transcription factor 6 beta

GeneMGI:105121Synonyms: Creb-rp, ATF6beta, +1 more

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Integument Mortality/aging

19 No significant impact

3 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

scaly skin1 supporting datasetAtf6btm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
preweaning lethality, incomplete penetrance3 supporting datasetsAtf6btm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetAtf6btm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Atf6btm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Atf6btm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Atf6btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Atf6btm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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