Nin | ninein

GeneMGI:105108Synonyms: 3110068G20Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Nervous system Hearing/vestibular/ear Behavior/neurological

14 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:152Adult tissues
50Embryo tissues

Phenotypes

abnormal auditory brainstem response5 supporting datasetsNintm1b(EUCOMM)HmguhomozygoteEarly adult1.48x10-6 
decreased prepulse inhibition5 supporting datasetsNintm1b(EUCOMM)HmguhomozygoteEarly adult7.36x10-34 
hyperactivity9 supporting datasetsNintm1b(EUCOMM)HmguhomozygoteEarly adult1.75x10-13 
decreased anxiety-related response1 supporting datasetNintm1b(EUCOMM)HmguhomozygoteEarly adult5.35x10-9 
decreased startle reflex1 supporting datasetNintm1b(EUCOMM)HmguhomozygoteEarly adult4.91x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nintm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Nintm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Nintm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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