Gpx3 | glutathione peroxidase 3

GeneMGI:105102Synonyms: EGPx, plasma GPx, +2 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetGpx3tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetGpx3tm1b(KOMP)WtsihomozygoteE15.5N/A * 
impaired glucose tolerance1 supporting datasetGpx3tm1b(KOMP)WtsiheterozygoteEarly adult7.07x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Gpx3tm1(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Gpx3tm1.1(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)ES Cell
mouse
Gpx3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Gpx3tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Gpx3tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Gpx3tm357974(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Gpx3tm41205(L1L2_st0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter