Gpx3 | glutathione peroxidase 3

GeneMGI:105102Synonyms: EGPx, plasma GPx, +2 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetGpx3tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetGpx3tm1b(KOMP)WtsihomozygoteE15.5N/A * 
impaired glucose tolerance1 supporting datasetGpx3tm1b(KOMP)WtsiheterozygoteEarly adult7.07x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gpx3tm1(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (with selection cassette)es cell
mouse
Gpx3tm1.1(EGFP/cre/ERT2)WtsiReporter-tagged deletion allele (post Cre, with no selection cassette)es cell
mouse
Gpx3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Gpx3tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Gpx3tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Gpx3tm357974(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Gpx3tm41205(L1L2_st0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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