Slc6a5 | solute carrier family 6 (neurotransmitter transporter, glycine), member 5

GeneMGI:105090Synonyms: Glyt2

Physiological systems

22 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Hematopoietic system Skeleton Mortality/aging

19 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:73Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Slc6a5^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal lumbar vertebrae morphology	1 supporting dataset	Slc6a5^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.27x10^-8
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Slc6a5^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	8.33x10^-6
abnormal sacral vertebrae morphology	1 supporting dataset	Slc6a5^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.27x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc6a5.

Associated images

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Histopathology

There is no histopathology data found for Slc6a5.

IMPC related publications

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External links

No external links available for Slc6a5.

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*Slc6a5^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Slc6a5^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse

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