Pou2af1 | POU domain, class 2, associating factor 1

GeneMGI:105086Synonyms: OCA-B, OCAB, +5 more

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Immune system Hematopoietic system

19 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

1Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased neutrophil cell number	1 supporting dataset	Pou2af1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.63x10^-15
decreased spleen weight	1 supporting dataset	Pou2af1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.16x10^-5
decreased lymphocyte cell number	2 supporting datasets	Pou2af1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.05x10^-13

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pou2af1.

Associated images

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Histopathology

There is no histopathology data found for Pou2af1.

IMPC related publications

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External links

No external links available for Pou2af1.

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*Pou2af1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pou2af1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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