Hsd17b1 | hydroxysteroid (17-beta) dehydrogenase 1
Physiological systems
17 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system
9 No significant impact
7 Not tested
Data collections
Gene metrics:18Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| abnormal motor coordination/balance | 1 supporting dataset | Hsd17b1tm1.1(KOMP)Vlcg | homozygote | Early adult | 5.28x10-6 | ||
| decreased vertical activity | 1 supporting dataset | Hsd17b1tm1.1(KOMP)Vlcg | homozygote | Early adult | 2.47x10-5 | ||
| abnormal sleep behavior | 4 supporting datasets | Hsd17b1tm1.1(KOMP)Vlcg | homozygote | Early adult | 5.95x10-11 | ||
| decreased total body fat amount | 1 supporting dataset | Hsd17b1tm1.1(KOMP)Vlcg | homozygote | Early adult | 8.36x10-5 | ||
| abnormal lens morphology | 1 supporting dataset | Hsd17b1tm1.1(KOMP)Vlcg | homozygote | Early adult | 4.72x10-15 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Hsd17b1tm1.1(KOMP)Vlcg | homozygote | Early adult | 5.09x10-17 | ||
| decreased mean corpuscular volume | 1 supporting dataset | Hsd17b1tm1.1(KOMP)Vlcg | homozygote | Early adult | 1.53x10-5 | ||
| increased bone mineral content | 2 supporting datasets | Hsd17b1tm1.1(KOMP)Vlcg | homozygote | Early adult | 7.17x10-6 | ||
| increased circulating potassium level | 1 supporting dataset | Hsd17b1tm1.1(KOMP)Vlcg | homozygote | Early adult | 4.86x10-8 | ||
| decreased circulating chloride level | 1 supporting dataset | Hsd17b1tm1.1(KOMP)Vlcg | homozygote | Early adult | 4.12x10-5 |
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External links
No external links available for Hsd17b1.
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