Tnni2 | troponin I, skeletal, fast 2
GeneMGI:105070
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Adipose tissue Mortality/aging
15 No significant impact
5 Not tested
Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:42Adult tissues
29Embryo tissues
| preweaning lethality, complete penetrance | 6 supporting datasets | Tnni2tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| decreased total body fat amount | 1 supporting dataset | Tnni2tm1.1(KOMP)Vlcg | heterozygote | Early adult | 5.4x10-8 | ||
| decreased circulating glucose level | 1 supporting dataset | Tnni2tm1.1(KOMP)Vlcg | heterozygote | Early adult | 5.06x10-5 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Tnni2tm1.1(KOMP)Vlcg | heterozygote | Early adult | 7.5x10-5 | ||
| abnormal skin morphology | 1 supporting dataset | Tnni2tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * |
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External links
No external links available for Tnni2.
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| Tnni2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Tnni2tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Tnni2tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Tnni2tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |