Rab10 | RAB10, member RAS oncogene family
GeneMGI:105066
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological Mortality/aging
12 No significant impact
7 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Rab10em1(IMPC)J | heterozygote | Early adult | 2.62x10-12 | ||
| iris synechia | 1 supporting dataset | Rab10em1(IMPC)J | heterozygote | Early adult | 4.56x10-21 | ||
| decreased mean corpuscular volume | 1 supporting dataset | Rab10em1(IMPC)J | heterozygote | Early adult | 3.15x10-10 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Rab10em1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal auditory brainstem response | 1 supporting dataset | Rab10em1(IMPC)J | heterozygote | Early adult | 9.23x10-7 | ||
| increased startle reflex | 1 supporting dataset | Rab10em1(IMPC)J | heterozygote | Early adult | 4.56x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Rab10em1(IMPC)J | homozygote | E9.5 | N/A * |
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External links
No external links available for Rab10.
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| Rab10em1(IMPC)J | Exon Deletion | | mouse |
| Rab10tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Rab10tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |