Ubp1 | upstream binding protein 1

GeneMGI:104889Synonyms: NF2d9, LBP-1b, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Embryo Growth/size/body region Mortality/aging

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased circulating calcium level	1 supporting dataset	Ubp1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	9.18x10^-5
increased circulating creatinine level	1 supporting dataset	Ubp1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	8.94x10^-5
pallor	1 supporting dataset	Ubp1^{tm1b(KOMP)Mbp}	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Ubp1^{tm1b(KOMP)Mbp}	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Ubp1^{tm1b(KOMP)Mbp}	homozygote	E12.5	N/A ^*
decreased circulating alkaline phosphatase level	1 supporting dataset	Ubp1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	2.19x10^-6
pale yolk sac	1 supporting dataset	Ubp1^{tm1b(KOMP)Mbp}	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Ubp1^{tm1b(KOMP)Mbp}	homozygote	E9.5	N/A ^*
decreased circulating serum albumin level	1 supporting dataset	Ubp1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	7.06x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ubp1.

Associated images

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Histopathology

There is no histopathology data found for Ubp1.

IMPC related publications

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External links

No external links available for Ubp1.

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*Ubp1^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ubp1^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ubp1^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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