Runx1t1 | RUNX1 translocation partner 1

GeneMGI:104793Synonyms: MTG8, Cbfa2t1h, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

1Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Runx1t1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased circulating triglyceride level	1 supporting dataset	Runx1t1^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.48x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Runx1t1.

Associated images

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Histopathology

There is no histopathology data found for Runx1t1.

IMPC related publications

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External links

No external links available for Runx1t1.

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*Runx1t1^{tm171(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Runx1t1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Runx1t1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Runx1t1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes