Adam5 | a disintegrin and metallopeptidase domain 5

GeneMGI:104730Synonyms: tMDCII

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Reproductive system Hematopoietic system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular volume1 supporting datasetAdam5em1(IMPC)JhomozygoteEarly adult8.48x10-6 
male infertility1 supporting datasetAdam5em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Adam5em1(IMPC)JExon Deletionmouse
Adam5tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Adam5tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Adam5tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Adam5tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Adam5tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Adam5tm3a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Adam5tm3e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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