Eps8 | epidermal growth factor receptor pathway substrate 8

GeneMGI:104684

Physiological systems

14 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological

11 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased vertical activity	2 supporting datasets	Eps8^tm1Ppdf	homozygote	Early adult	4.99x10^-5
decreased body temperature	1 supporting dataset	Eps8^tm1Ppdf	homozygote	Early adult	7.19x10^-5
decreased body weight	1 supporting dataset	Eps8^tm1Ppdf	homozygote	Early adult	6.49x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Eps8.

Associated images

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Histopathology

There is no histopathology data found for Eps8.

IMPC related publications

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External links

No external links available for Eps8.

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*Eps8^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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