Fnta | farnesyltransferase, CAAX box, alpha

GeneMGI:104683Synonyms: FTA

Physiological systems

22 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Pigmentation Integument Mortality/aging

19 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:74Adult tissues

30Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic lethality prior to organogenesis	1 supporting dataset	Fnta^{tm1b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Fnta^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	2 supporting datasets	Fnta^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal coat/hair pigmentation	3 supporting datasets	Fnta^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.76x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fnta.

Associated images

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Histopathology

There is no histopathology data found for Fnta.

IMPC related publications

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External links

No external links available for Fnta.

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*Fnta^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Fnta^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Fnta^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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