Hmmr | hyaluronan mediated motility receptor (RHAMM)
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Limbs/digits/tail Vision/eye Skeleton Mortality/aging
14 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Hmmrtm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal retina outer nuclear layer morphology | 2 supporting datasets | Hmmrtm1b(EUCOMM)Hmgu | homozygote | Early adult | 1.07x10-9 | ||
| increased bone mineral density | 1 supporting dataset | Hmmrtm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.64x10-5 | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Hmmrtm1b(EUCOMM)Hmgu | homozygote | Early adult | 2.07x10-5 | ||
| short tibia | 1 supporting dataset | Hmmrtm1b(EUCOMM)Hmgu | homozygote | Early adult | 4.45x10-5 | ||
| decreased total retina thickness | 2 supporting datasets | Hmmrtm1b(EUCOMM)Hmgu | homozygote | Early adult | 9.27x10-7 |
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External links
No external links available for Hmmr.
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| Hmmrtm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Hmmrtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Hmmrtm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Hmmrtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |