Penk | preproenkephalin
Physiological systems
18 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Skeleton
11 No significant impact
6 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:152Adult tissues
25Embryo tissues
| abnormal bone structure | 1 supporting dataset | Penktm1(KOMP)Mbp | homozygote | Early adult | 2.01x10-6 | ||
| absent testes | 1 supporting dataset | Penktm1(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| increased total body fat amount | 1 supporting dataset | Penktm1(KOMP)Mbp | homozygote | Early adult | 8.48x10-5 | ||
| decreased bone mineral content | 1 supporting dataset | Penktm1(KOMP)Mbp | homozygote | Early adult | 5.07x10-6 | ||
| abnormal retina morphology | 1 supporting dataset | Penktm1(KOMP)Mbp | homozygote | Early adult | 4.77x10-5 | ||
| decreased locomotor activity | 1 supporting dataset | Penktm1(KOMP)Mbp | homozygote | Early adult | 9.15x10-6 | ||
| decreased body length | 1 supporting dataset | Penktm1(KOMP)Mbp | homozygote | Early adult | 6.42x10-5 |
| | | | | | | | | | |
External links
No external links available for Penk.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Penktm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Penktm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Penktm429447(L1L2_GT0_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |