Ccr3 | C-C motif chemokine receptor 3

GeneMGI:104616Synonyms: MIP-1 alphaRL2, CC-CKR3, +2 more

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal heart morphology1 supporting datasetCcr3em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged spleen2 supporting datasetsCcr3em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetCcr3em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetCcr3em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetCcr3em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal cornea morphology1 supporting datasetCcr3em1(IMPC)CcpczhomozygoteEarly adult1.45x10-6 
abnormal spleen morphology2 supporting datasetsCcr3em1(IMPC)CcpczhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ccr3em1(IMPC)CcpczWhole-gene deletionmouse
Ccr3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Ccr3tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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