Rab34 | RAB34, member RAS oncogene family

GeneMGI:104606Synonyms: Narr, Rah1

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Digestive/alimentary Vision/eye Craniofacial Mortality/aging Cardiovascular system

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

1Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



edema	1 supporting dataset	Rab34^{tm1b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
polydactyly	1 supporting dataset	Rab34^{tm1b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
increased heart weight	1 supporting dataset	Rab34^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.89x10^-5
cleft palate	1 supporting dataset	Rab34^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
anophthalmia	1 supporting dataset	Rab34^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
abnormal limb morphology	1 supporting dataset	Rab34^{tm1b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
abnormal limb bud morphology	1 supporting dataset	Rab34^{tm1b(EUCOMM)Hmgu}	homozygote	E12.5	N/A ^*
facial cleft	1 supporting dataset	Rab34^{tm1b(EUCOMM)Hmgu}	homozygote	E18.5	N/A ^*
polydactyly	1 supporting dataset	Rab34^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*
edema	1 supporting dataset	Rab34^{tm1b(EUCOMM)Hmgu}	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rab34.

Associated images

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Histopathology

There is no histopathology data found for Rab34.

IMPC related publications

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External links

No external links available for Rab34.

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*Rab34^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Rab34^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rab34^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rab34^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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